Box 2.

High-risk criteria set out by ESC in the management and for evaluation of invasive angiography in patients presenting with NSTEMI.7

Primary criteria:
> relative rise or fall in troponin
> dynamic ST-T wave changes (with or without symptoms)
> GRACE score >140.
Secondary criteria:
> diabetes mellitus
> renal insufficiency (eGFR <60 mL/min/1.73 m2)
> early post-infarction angina
> recent PCI
> previous CABG
> intermediate or high GRACE risk score.
NB: This is different to the GRACE score (for GRACE score visit CABG = coronary artery bypass surgery; eGFR = estimated glomerular filtration rate; ESC = European Society of Cardiology; GRACE = Global Registry of Acute Coronary Events; PCI = percutaneous coronary intervention