Table 1.

Drugs commonly causing SJS/TEN.

GroupDrugs
AntibacterialsSulphonamides, penicillins, cephalosporins, quinolones, vancomycin
AnticonvulsantsPhenytoin, carbamazepine, phenobarbitone, valproate, lamotrigine
NSAIDsAspirin, piroxicam, diclofenac, phenylbutazone
AntiretroviralsNevirapine, protease inhibitors, abacavir
AntituberculousIsoniazid, ethambutol
AntigoutAllopurinol
AntimalarialsChloroquine

  • NSAIDs = non-steroidal anti-inflammatory drugs; SJS = Stevens–Johnson syndrome; TEN = toxic epidermal necrolysis.