Box 1.

Inclusion criteria for potential cases of DRESS.22

> hospitalisation
> reaction suspected to be drug related
> acute skin rash
> fever >38°C
> enlarged lymph nodes at ≥2 sites
> involvement of ≥1 internal organ
> blood count abnormalities
> lymphocytes above or below the laboratory limits
> eosinophils above the laboratory limits
> platelets below the laboratory limits.