Variables with evidence of linear change over time.
| Estimate | Standard error | p value | |
|---|---|---|---|
| pH | 0.19 | 0.027 | <0.0001 |
| HCO 3 (mmol/L) | 6.13 | 1.65 | 0.0013 |
| Base excess (mmol/L) | 9.67 | 1.65 | <0.0001 |
| Anion gap (mmol/L) | –5.13 | 1.33 | 0.0010 |
| APTT (s) | 1.64 | 0.73 | 0.037 |
APTT = activated partial thromboplastin time.