Antihypertensive drugs in pregnancy
| 1st choice | Alternative first-line | Second-line | Third-line | Contraindicated in pregnancy |
|---|---|---|---|---|
| Labetalol | Nifedipine (MR) | Methyldopa | Doxazosin | ACE inhibitors (safe when breastfeeding*) |
| Amlodipine | Hydralazine | Angiotensin II receptor antagonists Spironolactone | ||
| Selective β-blockers |
*Avoid in acute kidney injury. Enalapril and captopril are the preferred agents, as safety data are limited for other drugs in this class.
ACE = angiotensin-converting enzyme; MR = modified release