A sample schedule for subcutaneous immunotherapy
| Dilution | Concentration, SQU*/mL | Volume, mL | Dosage, SQU* |
|---|---|---|---|
| 1:1,000 | 100 | 0.2 | 20 |
| 0.4 | 40 | ||
| 0.8 | 80 | ||
| 1:100 | 1,000 | 0.2 | 200 |
| 0.4 | 400 | ||
| 0.8 | 800 | ||
| 1:10 | 10,000 | 0.2 | 2,000 |
| 0.4 | 4,000 | ||
| 0.8 | 8,000 | ||
| 1:1 | 100,000 | 0.1 | 10,000 |
| 0.2 | 20,000 | ||
| 0.4 | 40,000 | ||
| 0.6 | 60,000 | ||
| 0.8 | 80,000 | ||
| 1.0 | 100,000 | ||
| Maintenance phase | 3–5 years | 1.0 | 100,000 |
*SQU (standard quality units) is used here as a generic term to indicate standardisation of allergen content, but the specific units and the amount of allergen varies depending on the type of allergen and the manufacturer. The conventional schedule for subcutaneous immunotherapy with unmodified allergen extracts consists of a dose build up by means of 1-weekly injections, followed by maintenance dose injections at 4–8 week intervals. Rapid up-dosing is possible with a rush protocol.