Table 1.

Uses and pitfalls of imaging techniques in acute ischaemic stroke35,36

TechniqueUses/benefitsPitfalls
Non-contrast CT headWidely available and quick to performLow sensitivity (39%) for ischaemia, especially in posterior fossa
High sensitivity for acute haemorrhage
Specificity of 100% if ischaemia detected
CT angiogramNon-invasive assessment of intracranial and extracranial circulationUnreliable in differentiating stroke from mimic (only a minority of strokes will have large artery occlusion)
Can confirm large vessel occlusion to guide clot retrieval strategies in patients with high NIHSS scores
Diffusion-weighted magnetic resonance imagingAbnormalities on diffusion-weighted sequences strongly support diagnosis of strokeRestricted diffusion can be seen in tumours, cerebral infections and following seizure activity
Sensitivity for detection of acute stroke up to 99% with specificity of 92%Patient instability and claustrophobia can limit suitability of scan
Requires more time for scanning than CT
  • CT = computerised tomography; NIHSS = National Institute of Health Stroke Scale