Goal of minimal correction of plasma sodium in first 24 hours (mmol/L) | Limits not to exceed in plasma sodium per 24 hours (mmol/L) | |
---|---|---|
Normal risk patient | 4–8 | 10–12* |
High risk of ODS | 4–6 | 8 |
Patients with pNa+ <105 mmol/L, hypokalaemia, alcoholism, malnutrition, liver disease |
*Not >18 mmol/L in 48 hours in normal risk patients.
ODS = osmotic demyelination syndrome