Anterior pituitary hormones
| Investigation | Result | Reference range |
|---|---|---|
| Growth hormone | 0.03 μg/L | 0.13-9.9 μg/L |
| Cortisol (random) | 48 nmol/L | AM 171–536 nmol/L |
| PM 64–327 nmol/L | ||
| LH | <0.5 IU/L | 8–59 U/L (menopausal) |
| FSH | <0.5 IU/L | 26–135 U/L (menopausal) |
| TSH | 0.73 mIu/L | 0.27–4.2 mIu/L |
| FT4 | 6.3 pmol/L | 12.0–22.0 pmol/L |
| T3 | 0.44 nmol/L | 1.3-3.1 nmol/L |
| Total prolactin | 184 mU/L | 102-496 mU/L |
FSH = follicle stimulating hormone; FT4 = free thyroxine; LH = luteinising hormone; TSH = Thyroid-stimulating hormone.
Investigation of pituitary function showing cortisol insufficiency, undetectable gonadotropins in a postmenopausal female, secondary hypothyroidism and normal prolactin, consistent with hypopituitarism. Previous oestradiol, FSH/LH levels sent from primary care reviewed retrospectively were consistent with hypogonadotrophic hypogonadism, suggesting pituitary dysfunction preceded this presentation by a number of years. At the time of writing, growth hormone levels were not detectable but the patient had not yet undergone dynamic pituitary function testing to confirm growth hormone deficiency.