Table 1.

Diagnostic criteria for obesity hypoventilation syndrome

CriteriaDescription
ObesityBody mass index >30 kg/m2
HypoventilationAwake arterial hypercapnia (PaCO2 >45 mmHg)
Sleep-disordered breathingPolysomnography reveals sleep hypoventilation with nocturnal hypercapnia with or without obstructive apnea/hypopnea events
Rule out other causes of hypoventilationSevere chronic obstructive pulmonary disease, severe interstitial lung disease, chest wall disorders, thyroid disorders and congenital hypoventilation syndromes