Table 1.

Properties of compounds used in selective internal radiation therapy

TheraSpheresSIR-SpheresQuiremSpheres
Size, μm20–3020–6020–50
IsotopeYttrium-90 in glass matrixYttrium-90 adsorbed on resin surfaceHolmium-166 on PLLA (poly-L-lactic acid)
Radiation emittedbeta (β)beta (β)beta (β) and low energy gamma (γ)
Physical half-life (T 1/2)64 hours64 hours26.8 hours
Activity per sphere, Bq250050450
Number of particles∼1–8×10 6∼40–80×10 633×10 6
Angiographic monitoringNoNecessary (potential reflux)Necessary (potential reflux)