Cohort characteristics
| Statin user n=633 | Non-user n=1,434 | Total, n (%) | p-value | |
|---|---|---|---|---|
| n (%) | 633 (30.7) | 1,434 (69.3) | 2,067 | |
| Mean age ± SD, years | 75.66±11.7 | 69.2±20.1 | <0.001 | |
| Gender, n (%) | ||||
| Male | 355 (56.2) | 691 (48.2) | 1,046 (50.6) | 0.001 |
| Female | 278 (43.8) | 743 (51.8) | 1,021 (49.4) | |
| Patient outcome, n (%) | ||||
| Survived | 526 (83.1) | 1,083 (75.5) | 1,609 (77.9) | <0.001 |
| Died | 107 (16.9) | 351 (24.5) | 458 (22.1) | |
| Diabetes status, n (%) | ||||
| Yes | 230 (36.4) | 174 (12.1) | 404 (19.6) | <0.001 |
| No | 403 (63.6) | 1,260 (87.9) | 1,663 (80.4) | |
| Mean length of stay ± SD, days | 13.5±15.2 | 8.7±12.7 | <0.001 | |
| ICU admission, n (%) | ||||
| Yes | 67 (10.6) | 102 (7.1) | 169 (8.1) | 0.008 |
| No | 567 (89.4) | 1,331 (92.9) | 1,898 (91.9) | |
| Mean ICU length of stay ± SD, days | 8.6±10.3 | 7.7±8.9 | 169 (8.1) | 0.483 |
| Median CURB-65 score (IQR) | 2 (2–2) | 2 (1–3) | 2,006 (97) | <0.001 |
| Median CRP median, mg/L (IQR) | 93 (34–211) | 102 (43–215) | 1,801 (87) | 0.188 |
| Median WCC, ×10 9/L (IQR) | 12.8 (9.3–16.5) | 12.6 (8.9–16.9) | 1,573 (76) | 0.709 |
| Median urea, mmol/L (IQR) | 8.6 (6.1–12.3) | 7.3 (4.9–11.3) | 2,006 (97) | <0.001 |
CRP = C-reactive protein; ICU = intensive care unit; IQR = interquartile range; SD = standard deviation; WCC = white cell count