Relationship between simvastatin dose and mortality
| n | B | SE | OR | (95% CI) | p-value | |
|---|---|---|---|---|---|---|
| Simvastatin dose | ||||||
| 10 mg | 15 | 4.346 | 0.825 | 77.189 | (15.331–388.634) | <0.001 |
| 20 mg | 76 | 3.019 | 0.351 | 20.472 | (10.285–40.747) | <0.001 |
| 40 mg | 352 | |||||
| 80 mg | 36 | –1.003 | 1.054 | 0.367 | (0.046–2.893) | 0.341 |
Relationship assessed by logistic regression and adjusted for age and disease severity (CURB-65 score). To assess the effect on mortality of increasing doses of simvastatin, patients taking 10 mg, 20 mg and 80 mg were compared to those on 40 mg.
B = regression coefficient; CI = confidence interval; OR = odds ratio; SE = standard error