Table 2.

Opioid equianalgesic ratiosa

Conversion (from PO morphine)Potency (compared with PO morphine)Example
Codeine PO0.1Codeine 240 mg PO = morphine 24 mg PO
Tramadol PO0.1–0.2Tramadol 400 mg/24 h PO = morphine 40–80 mg/24 h PO
Oxycodone PO1.5–2Morphine 60 mg/24 h PO = oxycodone 30–40 mg/24 h PO
Buprenorphine TD70–115Morphine 40–60 mg/24 h PO = buprenorphine 600 mcg/24 h = 25 mcg/h patch
Fentanyl TD100–150Morphine 60–90 mg/24 h PO = fentanyl 600 mcg/24 h = 25 mcg/h patch
Morphine SC2Morphine 60 mg/24 h PO = morphine 30 mg/24 h SC
  • aModified with permission from the Palliative Care Formulary 6th edition, palliativedrugs.com Ltd, Nottingham, UK. Some conversions are not agreed upon and expert opinion/local practice thus varies. PO = oral; TD = transdermal; SC = subcutaneous