Conversion (from PO morphine) | Potency (compared with PO morphine) | Example |
---|---|---|
Codeine PO | 0.1 | Codeine 240 mg PO = morphine 24 mg PO |
Tramadol PO | 0.1–0.2 | Tramadol 400 mg/24 h PO = morphine 40–80 mg/24 h PO |
Oxycodone PO | 1.5–2 | Morphine 60 mg/24 h PO = oxycodone 30–40 mg/24 h PO |
Buprenorphine TD | 70–115 | Morphine 40–60 mg/24 h PO = buprenorphine 600 mcg/24 h = 25 mcg/h patch |
Fentanyl TD | 100–150 | Morphine 60–90 mg/24 h PO = fentanyl 600 mcg/24 h = 25 mcg/h patch |
Morphine SC | 2 | Morphine 60 mg/24 h PO = morphine 30 mg/24 h SC |
↵aModified with permission from the Palliative Care Formulary 6th edition, palliativedrugs.com Ltd, Nottingham, UK. Some conversions are not agreed upon and expert opinion/local practice thus varies. PO = oral; TD = transdermal; SC = subcutaneous