Comparison of workload (ie number of cases predicted to be at risk of acute kidney injury; AKI) and sensitivity analysis of index and maximum National Early Warning Score (NEWS) models at different predicted probability thresholds for NEWS 0–6a
| Predicted probability of AKI | Index NEWS | Index NEWS-only model (A0) | Index NEWS model (A3) | Maximum NEWS model (B3) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| %Sens. | %Spec. | PPV% | Workload n (%) | %Sens. | %Spec. | PPV% | Workload n (%) | %Sens. | %Spec. | PPV% | Workload n (%) | ||
| 0.0337 | 1 | 87.22 | 20.09 | 4.40 | 26,956 (80.20) | 80.75 | 46.17 | 5.95 | 18,457 (54.92) | 78.99 | 61.26 | 7.92 | 13,567 (40.37) |
| 0.0373 | 2 | 66.13 | 48.11 | 5.10 | 17,632 (52.46) | 76.46 | 51.16 | 6.12 | 16,778 (49.92) | 75.75 | 64.59 | 8.28 | 12,450 (37.05) |
| 0.0413 | 3 | 36.59 | 75.23 | 5.87 | 8,484 (25.25) | 69.88 | 56.32 | 6.32 | 15,038 (44.75) | 72.96 | 67.48 | 8.65 | 11,480 (34.16) |
| 0.0457 | 4 | 27.11 | 83.08 | 6.33 | 5,825 (17.33) | 63.56 | 62.12 | 6.61 | 13,079 (38.89) | 70.24 | 74.63 | 9.12 | 10,480 (31.18) |
| 0.0506 | 5 | 19.84 | 88.13 | 6.59 | 4,099 (12.20) | 55.33 | 68.13 | 6.83 | 11,029 (32.81) | 67.60 | 73.14 | 9.60 | 9,581 (28.51) |
| 0.0560 | 6 | 13.96 | 92.01 | 6.87 | 2,765 (8.22) | 46.95 | 74.27 | 7.15 | 89,35 (26.59) | 63.26 | 75.74 | 9.91 | 8,685 (25.84) |
↵aPPV = positive predictive value; Sens = sensitivity; Spec = specificity