Table 2.

Infections requiring antibiotics, including type, course length, and percentage of excess treatment

System infectedInfectionNumber of patientsMedian inpatient antibiotic duration days (range days)Median total antibiotic course days (course length range in days)Trust recommended duration (days)Median days of therapy received for infection / recommended (percentage excess)
Skin and soft tissueDog bite13 (NA)10 (10)710/7 (43%)
Facial cellulitis24.5 (2–7)7 (7)107/10 (–30%)
Orbital cellulitis15 (n/a)12 (n/a)1012/10 (20%)
Cellulitis115 (n/a)15 (n/a)7–1015/10 (50%)
SepsisSource unknown adult76 (4–11)7(5–11)77/7 (0%)
ObstetricsIntrapartum pyrexia22.5 (2–3)7.5 (7–8)77.5/7 (7%)
RespiratoryHAP217 (2–35)8 (6–35)78/7 (14%)
IECOPD35 (2–9)7 (5–9)57/5 (40%)
Bronchitis85.5 (2–10)7 (2–17)77/7 (0%)
Aspiration pneumonia17 (n/a)7 (n/a)77/7 (0%)
GastrointestinalDiverticulitis44 (1–4)6 (5–8)76/7 (–14%)
Intra-abdominal infection25.5 (5–6)9 (5–13)79/7 (28%)
GDH+15 (n/a)5 (n/a)n/an/a
Cholangitis34 (4–6)6 (4–11)76/7 (–14%)
Cholecystitis34 (3–7)6 (5–15)76/7 (–14%)
ENTMastoiditis13 (n/a)13 (n/a)7–14Within range
Acute otitis media12 (n/a)12 (n/a)712/7 (71%)
OthersJoint replacement, prophylaxis16 (n/a)6 (n/a)16/1 (600%)
Suspected neonatal sepsis13 (n/a)3 (n/a)48 hours then reviewn/a
Diabetic foot17 (n/a)n/aUp to 3 monthsWithin range
Multiple lung abscesses12 (n/a)13 (n/a)14 Seek micro advicen/a
Surgical wound infection111 (n/a)11 (n/a)48 hours then reviewn/a
Tooth infection19 (n/a)9 (n/a)79/7 (28%)
Cystic fibrosis exacerbation127 (n/a)27 (n/a)1427/14 (93%)
Orchitis15 (n/a)12 (n/a)1412/14 (–14%)
Tubo-ovarian abscess135 (n/a)75/7 (–29%)
Severe CAP10-8.5 (3–31)7–10 8.5/10 (–15%)
Non-severe CAP23-9 (3–24)5–79/7 (29%)
Lower UTI1-3 (n/a)3n/a
Upper UTI5-4 (3–15)7–104/10 (–60%)
CAUTI5-5 (3–10)75/7 (–29%)
  • CAP = community-acquired pneumonia; CAUTI = catheter-associated urinary tract infection; CF = cystic fibrosis; GDH = glutamic acid dehydrogenase (C difficile); HAP = hospital-acquired pneumonia; IECOPD = infective exacerbation of chronic obstructive disease; UTI = urinary tract infection, NA = not available