Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of conventional and age adjusted D-dimer (value and 95% confidence interval)
| Conventional D-dimer | Age-adjusted D-dimer | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Age group | Number | Sensitivity | Specificity | PPV | NPV | Sensitivity | Specificity | PPV | NPV |
| All ages | 329 | 1.00 (0.95–1.00) | 0.07 (0.04–0.11) | 0.22 (0.18–0.27) | 1.00 (0.81–1.00) | 0.97 (0.90–1.00) | 0.32 (0.27–0.38) | 0.28 (0.22–0.34) | 0.98 (0.92–1.00) |
| 50–59 | 59 | 1.00 (0.72–1.00) | 0.21 (0.10–0.35) | 0.22 (0.12–0.37) | 1.00 (0.69–1.00) | 1.00 (0.72–1.00) | 0.33 (0.20–0.48) | 0.26 (0.14–0.41) | 1.00 (0.79–1.00) |
| 60–69 | 90 | 1.00 (0.81–1.00) | 0.06 (0.02–0.14) | 0.21 (0.13–0.31) | 1.00 (0.40–1.00) | 1.00 (0.81–1.00) | 0.28 (0.18–0.40) | 0.26 (0.16–0.38) | 1.00 (0.83–1.00) |
| 70–79 | 96 | 1.00 (0.81–1.00) | 0.04 (0.01–0.11) | 0.19 (0.12–0.29) | 1.00 (0.29–1.00) | 0.94 (0.73–1.00) | 0.38 (0.28–0.50) | 0.26 (0.16–0.39) | 0.97 (0.83–1.00) |
| 80–89 | 68 | 1.00 (0.80–1.00) | 0.02 (0.00–0.10) | 0.25 (0.16–0.37) | 1.00 (0.02–1.00) | 0.94 (0.71–1.00) | 0.27 (0.16–0.42) | 0.30 (0.18–0.44) | 0.93 (0.68–1.00) |
| 90–99 | 16 | 1.00 (0.48–1.00) | 0.00 (0.00–0.28) | 0.31 (0.11–0.59) | n/a (0.00–1.00) | 1.00 (0.48–1.00) | 0.36 (0.11–0.69) | 0.42 (0.15–0.72) | 1.00 (0.40–1.00) |