Table 2.

Key clinical, test and implementation questions

ClinicalHow effective is FIT NPV as a rule out and can it be improved?
How often does FIT miss cancers?
Can a risk score be derived using the PPV?
TestIs there a difference between the tests?
What are appropriate cut-off levels?
What instructions should be given to patients and general practitioners?
ImplementationImpact of FIT on endoscopic services?
Acceptability to general practitioners and patients?
What are the barriers?
  • FIT = faecal immunochemical test; NPV = negative predictive value; PPV = positive predictive value.