Table 2.

Technical issues: a guide for when non-invasive ventilation is failing

ProblemCause(s)Solution (s)
Ventilator cycling independently of patient effortInspiratory trigger sensitivity is too highExcessive mask leakAdjust trigger

Reduce mask leak
Ventilator not triggering despite visible patient effortExcessive mask leakInspiratory trigger sensitivity too lowReduce mask leakAdjust triggerFor NM patients consider switch to PCV
Inadequate chest expansion despite apparent triggeringInadequate tidal volumeIncrease IPAP. In NM or chest wall disease consider longer Ti
Chest/abdominal paradoxUpper airway obstructionAvoid neck flexionIncrease EPAP
Premature expiratory effort by patientExcessive Ti or IPAPAdjust as necessary
  • EPAP = expiratory positive airway pressure; IPAP = inspiratory positive airway pressure; NIV = non-invasive ventilation; NM = neuromuscular; PCV = pressure-controlled ventilation; Ti = duration of inspiration. Reproduced with permission from Davidson AC, Banham S, Elliott M et al. BTS/ICS guideline for the ventilatory management of acute hypercapnic respiratory failure in adults. Thorax 2016;71 (Suppl 2):ii1–35.6