Table 2.

Summary of dietary interventions for weight loss

DietPrinciplesMechanisms of actionVariants
Low calorie diet800–1600 kcal/dayNegative energy balance (net deficit of calories)Cambridge diet
Weight Watchers
Nutrisystems diet
Intermittent Fasting
Biggest Loser
SlimFast
Jenny Craig
Very low calorie diet200–800 kcal/day
Low calorie diet: meal replacementPre-cooked low calorie meals
Low fat dietFat accounts for <30% of energy intakeNegative energy balance achieved by reduction of dietary fat, which is the most energy-dense macronutrient (9 kcal/g)LEARN
Ornish
Rosemary Conley
Low carbohydrate dietCarbohydrate intake <130 g/dayNegative energy balance achieved by reduction of dietary carbohydrates (3.75 kcal/g)
Mobilisation of glycogen stores and associated water loss
Ketogenesis
Atkins
South Beach
Zone
Very-low carbohydrate dietCarbohydrate intake <60 g/day
High protein dietProtein accounts for >30% of energy intakeIncreased satiety leading to reduced passive overconsumption of other macronutrients, thus achieving a lower energy balance
Mediterranean-style dietHigh intake of fruits, vegetables, grains; moderate intake of fat (mostly mono-unsaturated) and dairy (mostly cheese), reduced intake of meats (fish and poultry in preference to red meat)Lipid reduction
Lowering of oxidative stress and improved endothelial function
Anti-inflammatory effects
Gut microbiota changes
Regional variation