Suspected cause of nausea and vomiting | Examples | Recommended first-line antiemetic | Recommended second-line antiemetic |
---|---|---|---|
Chemical | Drugs, biochemical disturbance | Haloperidol | Levomepromazine |
Impaired gastric emptying | Gastric stasis, drugs | Metoclopramide | Levomepromazine |
Visceral/serosal | Bowel obstruction, constipation | Cyclizine | Levomepromazine |
Cranial | Space occupying lesion, radiotherapy | Cyclizine | Levomepromazine |
Vestibular | Base of skull tumour | Cyclizine | Levomepromazine |
Cortical | Anxiety, pain | Benzodiazepines | Levomepromazine |