Skip to main content

Advertisement

Log in

The prevalence of adrenal incidentaloma in routine clinical practice

  • Original Article
  • Published:
Endocrine Aims and scope Submit manuscript

Abstract

The prevalence of adrenal incidentaloma (AI) on computed tomography (CT) in the general population has been reported to be as high as 4.2%. However, many of the previous studies in this field utilised a prospective approach with analysis of CT scans performed by one or more radiologists with a specialist interest in adrenal tumours and a specific focus on identifying the presence of an adrenal mass. A typical radiology department, with a focus on the patient’s presenting complaint as opposed to the adrenal gland, may not be expected to diagnose as many adrenal incidentalomas as would be identified in a dedicated research protocol. We hypothesised that the number of AI reported in routine clinical practice is significantly lower than the published figures would suggest. We retrospectively reviewed the reports of all CT thorax and abdomen scans performed in our hospital over a 2 year period. 3,099 patients underwent imaging, with 3,705 scans performed. The median age was 63 years (range 18–98). Thirty-seven true AI were diagnosed during the time period studied. Twenty-two were diagnosed by CT abdomen (22/2,227) and 12 by CT thorax (12/1,478), a prevalence of 0.98 and 0.81% with CT abdomen and thorax, respectively, for AI in routine clinical practice.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. W.F. Young Jr, Clinical practice. The incidentally discovered adrenal mass. N. Engl. J. Med. 356(6), 601–610 (2007)

    Article  PubMed  CAS  Google Scholar 

  2. NIH state-of-the-science statement on management of the clinically inapparent adrenal mass (“incidentaloma”). NIH Consens. State Sci. Statements 2002 Feb 4-6;19(2):1–25

  3. A. Comlekci, S. Yener, S. Ertilav, M. Secil, B. Akinci, T. Demir, L. Kebapcilar, F. Bayraktar, S. Yesil, S. Eraslan, Adrenal incidentaloma, clinical, metabolic, follow-up aspects: single centre experience. Endocrine 37(1), 40–46 (2010)

    Article  PubMed  CAS  Google Scholar 

  4. S. Bovio, A. Cataldi, G. Reimondo, P. Sperone, S. Novello, A. Berruti, P. Borasio, C. Fava, L. Dogliotti, G.V. Scagliotti, A. Angeli, M. Terzolo, Prevalence of adrenal incidentaloma in a contemporary computerized tomography series. J. Endocrinol. Invest. 29(4), 298–302 (2006)

    PubMed  CAS  Google Scholar 

  5. E.V. Ferreira, M.A. Czepielewski, C.S. Faccin, M.C. Accordi, A.P. Furtado, Prevalence of adrenal incidentaloma at computed tomography (chest and abdominal) in a general hospital in Brazil. Arq. Bras. Endocrinol. Metabol. 49(5), 769–775 (2005)

    Article  PubMed  Google Scholar 

  6. M.F. Herrera, C.S. Grant, J.A. van Heerden, P.F. Sheedy, D.M. Ilstrup, Incidentally discovered adrenal tumors: an institutional perspective. Surgery 110(6), 1014–1021 (1991)

    PubMed  CAS  Google Scholar 

  7. L.S. Eldeiry, J.R. Garber, Adrenal incidentalomas, 2003 to 2005: experience after publication of the National Institutes of Health consensus statement. Endocr Pract 14(3), 279–284 (2008)

    PubMed  Google Scholar 

  8. J.H. Song, F.S. Chaudhry, W.W. Mayo-Smith, The incidental adrenal mass on CT: prevalence of adrenal disease in 1, 049 consecutive adrenal masses in patients with no known malignancy. AJR Am. J. Roentgenol. 190(5), 1163–1168 (2008)

    Article  PubMed  Google Scholar 

  9. Y. Erbil, N. Ozbey, U. Barbaros, H.R. Unalp, A. Salmaslioglu, S. Ozarmagan, Cardiovascular risk in patients with nonfunctional adrenal incidentaloma: myth or reality? World J. Surg. 33(10), 2099–2105 (2009)

    Article  PubMed  Google Scholar 

  10. M. Terzolo, A. Pia, A. Alì, G. Osella, G. Reimondo, S. Bovio, F. Daffara, M. Procopio, P. Paccotti, G. Borretta, A. Angeli, Adrenal incidentaloma: a new cause of the metabolic syndrome? J. Clin. Endocrinol. Metab. 87(3), 998–1003 (2002)

    Article  PubMed  CAS  Google Scholar 

  11. S. Midorikawa, H. Sanada, S. Hashimoto, T. Suzuki, T. Watanabe, The improvement of insulin resistance in patients with adrenal incidentaloma by surgical resection. Clin. Endocrinol. (Oxf.) 54(6), 797–804 (2001)

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Colin Davenport.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Davenport, C., Liew, A., Doherty, B. et al. The prevalence of adrenal incidentaloma in routine clinical practice. Endocrine 40, 80–83 (2011). https://doi.org/10.1007/s12020-011-9445-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12020-011-9445-6

Keywords

Navigation