CommentaryRole of D-dimers in diagnosis of venous thromboembolism
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Cited by (38)
Managing iliofemoral deep venous thrombosis of pregnancy with a strategy of thrombus removal is safe and avoids post-thrombotic morbidity
2014, Journal of Vascular SurgeryCitation Excerpt :D-dimer levels naturally increase during pregnancy and may also be elevated in certain pregnancy complications such as abruption, preeclampsia, and sepsis. As in most nonpregnant patients, the value of a D-dimer test is when it is normal, not when it is elevated.33 If DVT is suspected, LMWH or unfractionated heparin should be started immediately, especially if confirmatory diagnostic tests are delayed.
Early thrombus removal strategies for acute deep venous thrombosis: Clinical Practice Guidelines of the Society for Vascular Surgery and the American Venous Forum
2012, Journal of Vascular SurgeryCitation Excerpt :Routine use of the term proximal venous thrombosis should be discouraged in favor of more precise characterization of these thrombi as involving the iliofemoral or femoropopliteal venous segments. Several strategies for the diagnosis of DVT, incorporating combinations of clinical risk stratification,33,34 measurement of D-dimer levels,35-39 and venous ultrasound imaging, have been developed. As a component of such strategies, venous ultrasound imaging has become the most important diagnostic test for acute DVT.
Duration of anticoagulation for venous thromboembolism: Utility of D-dimers testing
2010, Immuno-Analyse et Biologie SpecialiseeAfrican-American ethnicity is associated with higher plasma levels of D-dimer in adults with hypertension
2009, Journal of Thrombosis and HaemostasisDiagnostic accuracy of the Triage<sup>®</sup> D-dimer test for exclusion of venous thromboembolism in outpatients
2008, Thrombosis ResearchCitation Excerpt :Despite its rapid and easy performance, each new DD assay should be validated clinically before its implementation in diagnostic strategies for exclusion of VTE. In the evaluation of VTE, the value of DD testing lies in its high sensitivity and high negative predictive value, thereby making it possible to avoid invasive and expensive imaging in a proportion of patients with negative DD results [13–19]. High sensitivity and high negative predictive value are primordial not to miss diagnosis because the mortality rate of PE is high [5,37].
Massive Pulmonary Embolism
2007, Cardiothoracic Critical Care