8Magnetic resonance imaging evaluation of small intestinal Crohn's disease
Section snippets
Contrast agents
Various contrast agents have been proposed for small bowel MRI applications.9, 10, 11, 17, 18 The most important characteristics of an intraluminal contrast agent suitable for intestinal application may be summarised as follows: uniform and homogeneous lumen opacification, a high contrast resolution between the lumen and bowel wall, a lack of significant adverse effects and low cost. In addition, minimal mucosal absorption and the absence of artefact formation are highly desirable for an
Crohn's disease
The diagnosis of Crohn's disease is established by combining clinical, imaging, endoscopic and histological features. The role of imaging has nowadays expanded to incorporate the classification of Crohn's disease subtypes. Accurate classification based on MRI findings can be achieved when using a technically demanding MRI examination protocol that can guarantee optimal luminal distension.
MRI using the oral administration of a contrast agent, referred to as magnetic resonance enterography, is
Summary
MRI currently contributes to the diagnostic assessment of small intestinal disease. Its most important advantages include superb soft tissue contrast, the ability to acquire functional information, direct multiplanar imaging and a lack of radiation exposure. Adequate bowel distension, homogeneous lumen opacification, fast sequences with breath-hold acquisition times, the use of both T1- and T2-weighted imaging and contrast enhancement are vital for optimal MRI examination. In particular, a
References (36)
- et al.
The small bowel enema: a ten year review
Clin Radiol
(1993) - et al.
The role of computed tomography in management of patients with Crohn disease
Clin Imaging
(1993) - et al.
Does a normal small-bowel enteroclysis exclude small-bowel disease? A long-term follow-up of consecutive normal studies
Abdom Imaging
(1994) - et al.
Computed tomography in the evaluation of Crohn disease
AJR Am J Roentgenol
(1983) - et al.
Serial observation in Crohn's disease: van hydro-MRI replace follow-through examinations?
Fortschr Röntgenstr
(1997) - et al.
MR imaging of Crohn disease: use of perflubron as a gastrointestinal contrast agent
J Magn Reson Imaging
(1994) - et al.
Small bowel MRI using water as a contrast medium
Br J Radiol
(1999) - et al.
MR imaging of the small bowel using water as a contrast agent in a preliminary study with healthy volunteers
AJR Am J Roentgenol
(1999) - et al.
Oral contrast agents in MRI of the gastrointestinal tract
Abdom Imaging
(2002) - et al.
Oral contrast agent for MRI of the bowel
Topics MRI
(2002)