Original articleClinical endoscopyHigh colonoscopic prevalence of proximal colon serrated polyps in average-risk men and women
Section snippets
Methods
The study was approved by the Institutional Review Board at Indiana University-Purdue University at Indianapolis. We performed secondary analyses using two databases. The first is the colonoscopy database that we previously described in our study about the variable endoscopic detection of proximal serrated polyps.15 In brief, this database is updated prospectively and includes procedure indications: patient age and sex; the presence or absence of colonic polyps; polyp size, location within the
Screening colonoscopy database
A total of 6681 screening colonoscopies were included (mean patient age 59 years; male 49%).15 Mean (± standard deviation [SD]) detection rates for adenomas, proximal adenomas, and proximal serrated polyps were 38% ± 7.8% (range 17%-47%), 28% ± 6.7% (13%-36%), and 13% ± 4.8% (1%-18%), respectively. There was no significant difference between the variances of the 3 detection rates (P = .41). The adenoma detection rate was significantly correlated with the serrated polyp detection rate
Discussion
This study shows that the prevalence of proximal serrated polyps, as approximated by the colonoscopy detection rates of high-level adenoma and serrated polyp detectors, is higher than previously thought. Approximately 1 in 5 average-risk screening colonoscopies yielded at least one proximal serrated polyp, a detection rate that was remarkably consistent between the two different databases that were used to derive this estimate of population prevalence. There was a strong correlation between
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DISCLOSURE: All authors disclosed no financial relationships relevant to this publication.
If you would like to chat with an author of this article, you may contact Dr Kahi at [email protected].
See CME section; p. 649.