ReviewTakotsubo cardiomyopathy or transient left ventricular apical ballooning syndrome: A systematic review
Section snippets
Background
Transient left ventricular apical ballooning syndrome (TLVABS) or takotsubo cardiomyopathy is an acute cardiac syndrome mimicking ST-segment elevation myocardial infarction that is characterized by transient wall-motion abnormalities extending beyond a single coronary distribution and involving apical and mid-portions of the left ventricle resembling the shape of a traditional Japanese octopus trap in the absence of significant obstructive coronary disease. It is typically observed in
Literature search
We reviewed published case series searching the MEDLINE database (through January 2007) as well as references from the reviewed full-length articles with no language restrictions that met the criteria depicted in Table 1. The following search terms were used: transient left ventricular apical ballooning syndrome, takotsubo cardiomyopathy, stress-induced cardiomyopathy, broken heart syndrome and ampulla cardiomyopathy. In case of more than one publication from the same Medical Center or the same
Results
The 28 case series that met the inclusion criteria for this systematic review comprised a total of 563 patients. 11 studies from Asia [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28] contributed 249 patients (44.2%), 14 studies from Europe [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42] 231 patients (41.0%), and 3 studies from North America [43], [44], [45] 83 patients (14.7%). Twelve studies were performed prospectively [20], [23], [25], [27],
Discussion
TLVABS is predominantly observed in postmenopausal women subsequent to a stressful event. Dramatic clinical presentation with substantial risk of complications in the acute setting is contrasting with complete recovery of the left ventricular function and favorable outcome in the majority of patients. Similar wall-motion dysfunctions extending beyond a single coronary distribution in the absence of obstructive coronary artery disease have also been demonstrated in patients with subarachnoid
References (69)
- et al.
Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome
Am J Cardiol
(2004) - et al.
Myocardial perfusion and fatty acid metabolism in patients with tako-tsubo-like left ventricular dysfunction
J Am Coll Cardiol
(2003) - et al.
Reversible myocardial contraction abnormalities in patients with an acute noncardiac illness
Chest
(1998) - et al.
Assessment of clinical features in transient left ventricular apical ballooning
J Am Coll Cardiol
(2003) - et al.
Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction
Am Heart J
(2002) - et al.
Evaluation of the arrhythmogenicity of stress-induced “takotsubo cardiomyopathy” from the time course of the 12-lead surface electrocardiogram
Am J Cardiol
(2003) - et al.
Transient left ventricular apical ballooning in a community hospital in Germany
Int J Cardiol
(2006) - et al.
Cardiovascular magnetic resonance findings in typical versus atypical forms of acute apical ballooning syndrome (takotsubo cardiomyopathy)
Int J Cardiol
(2007) - et al.
Incidence, clinical findings, and outcome of women with left ventricular apical ballooning syndrome
Am J Cardiol
(2007) - et al.
Transient left ventricular apical ballooning syndrome or takotsubo cardiomyopathy. About 11 cases
Ann Cardiol Angeiol
(2006)
Prevalence of tako-tsubo syndrome in a large urban agglomeration
Am J Cardiol
Tako-tsubo transient left ventricular apical ballooning is associated with a left anterior descending coronary artery with a long course along the apical diaphragmatic surface of the left ventricle
Rev Esp Cardiol
Electrocardiographic repolarization during stress from awakening on alarm call
J Am Coll Cardiol
Tako-tsubo cardiomyopathy (apical ballooning) with parvovirus B19 genome in endomyocardial biopsy
Int J Cardiol Mar 2
Acute beta-adrenergic overload produces myocyte damage through calcium leakage from the ryanodine receptor 2 (RYR2) but spares cardiac stem cells
J Biol Chem
Transient left ventricular apical ballooning syndrome without coronary stenosis: importance of the intraventricular pressure gradient
Rev Esp Cardiol
Transient cardiac apical ballooning syndrome: prevalence and clinical implications of right ventricular involvement
J Am Coll Cardiol
Takotsubo syndrome: a Bayesian approach to interpreting its pathogenesis
Mayo Clin Proc
Can takotsubo cardiomyopathy be familial?
Int J Cardiol
Transient midventricular ballooning syndrome
J Am Coll Cardiol
Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases
J Cardiol
Right ventricular involvement in takotsubo cardiomyopathy
Eur Heart J
Impact of earthquakes on takotsubo cardiomyopathy
JAMA
Electrocardiography cannot reliably differentiate transient left ventricular apical ballooning syndrome from anterior ST-segment elevation myocardial infarction
J Electrocardiol
Assessment of takotsubo cardiomyopathy (transient left ventricular apical ballooning) using 99m Tc-tetrofosmin, 123I-BMIPP, 123I-MIBG and 99mTc-PYP myocardial SPECT
Ann Nucl Med
123I-MIBG myocardial scintigraphy in patients with “takotsubo” cardiomyopathy
J Nucl Med
Tako-tsubo transient left ventricular apical ballooning: is intravascular ultrasound the key to resolve the enigma
Heart
Time course of electrocardiographic changes in patients with tako-tsubo syndrome
Circ J
Assessment of ampulla (takotsubo) cardiomyopathy with coronary angiography, two-dimensional echocardiography and 99 mTc-tetrofosmin myocardial single photon emission computed tomography
Ann Nucl Med
The clinical features of takotsubo cardiomyopathy
Q J Med
Plasma brain natriuretic peptide in takotsubo cardiomyopathy
Q J Med
A syndrome of transient left ventricular wall motion abnormality in the absence of coronary artery disease: a perspective from the United States
Cardiology
Clinical features of transient left ventricular apical ballooning
Am J Cardiol
High incidence of focal left ventricular wall motion abnormalities and normal coronary arteries in patients with myocardial infarctions presenting to a community hospital
J Invasive Cardiol
Cited by (411)
Ecological dynamics, ethnobotanical significance, and habitat projections for Arisaema costatum (Wall.) Mart. in response to climate change in Nepal
2024, Global Ecology and ConservationTakotsubo syndrome in the context of severe hypoglycemia
2022, Medicina ClinicaEpidemiology, Pathogenesis, and Clinical Course of Takotsubo Syndrome
2022, Heart Failure ClinicsAcute mitral regurgitation and cardiogenic shock: Reverse takotsubo cardiomyopathy or acute coronary syndrome?
2021, Journal of Cardiology CasesTwo case studies of cardiac arrest occurring in medically fit patients undergoing radical hysterectomy for cervical cancer
2021, Gynecologic Oncology Reports