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CASE REPORT: The Irony of Herbal Hepatitis: Ma-Huang-Induced Hepatotoxicity Associated with Compound Heterozygosity for Hereditary Hemochromatosis

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References

  1. Nadir A, Agrawal S, King PD, Marshall JB: Acute hepatitis associated with the use of a Chinese herbal product, Ma-Huang. Am J Gastroenterol 91(7):1436-1438, 1996

    Google Scholar 

  2. Yoshida EM, McLean CA, Cheng ES, Blanc PD, Somberg KA, Ferrell LD, Lake JR: Chinese herbal medicine, fulminant hepatitis and liver transplantation. AM J Gastronterol 91(12):2647-2648, 1996 (letter)

    Google Scholar 

  3. Stopman DR, Petty J, Ham J, Orloff S, Schwartz J: Weight loss supplements and Fulminant Hepatic Failure: A case series. Hepatology 36(4):168A, 2002 (abstract)

    Google Scholar 

  4. Fargion S, Stazi MA, Fracanzani AL, Mattioli M, Sampietro M, Tavazzi D, Bertelli C, Patriarca V, Mariani C, Fiorelli G: Mutations in the HFE gene and their interaction with exogenous risk factors in hepatocellular carcinoma. Blood Cells Mol Dis; 27(2):505-511, 2001

    Google Scholar 

  5. Stal P: Iron as a hepatotoxin. Dig Dis Sci 13(4):205-222, 1995

    Google Scholar 

  6. Smith BC, Grove J, Guzail MA, Day CP, Daly AK, Burt AD, Bassendine MF: Heterozygosity for hereditary hemochromatosis is associated with more fibrosis in chronic hepatitis C. Hepatology 27:1695-1699, 1998

    Google Scholar 

  7. George DK, Goldwurm S, MacDonald GA, Cowley LL, Walker NI, Ward PJ, Jazwinska EC, Powell LW: Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis. Gastroenterology 114(2):311-318, 1998

    Google Scholar 

  8. Karch SB: Ma huang and the Ephedra alkaloids. In Toxicology and Clinical Pharmacology of Herbal Products, 1st ed. MJ Cupp (ed). Totowa, New Jersey, Humana Press, 2000, pp 11-25

    Google Scholar 

  9. Astrup A, Toubro S, Cannon S, Hein P, Madsen J: Thermogenic synergism between ephedrine and caffeine in healthy volunteers: a double-blind, placebo-controlled study. Metabolism 40:323-329, 1991

    Google Scholar 

  10. FDA: www.fda.gov/bs/topics/NEWS/ephedra

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Bajaj, J., Knox, J.F., Komorowski, R. et al. CASE REPORT: The Irony of Herbal Hepatitis: Ma-Huang-Induced Hepatotoxicity Associated with Compound Heterozygosity for Hereditary Hemochromatosis. Dig Dis Sci 48, 1925–1928 (2003). https://doi.org/10.1023/A:1026105917735

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  • DOI: https://doi.org/10.1023/A:1026105917735

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