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Formation of 6-Aminopenicillanic Acid from Penicillin by Enzymatic Hydrolysis

Abstract

WE have found that enzymatic activity which brings about reaction (1) is fairly widespread among micro-organisms :

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References

  1. Sakaguchi, K., and Murao, S., J. Agric. Chem. Soc. (Japan), 23, 411 (1950).

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  2. Murao, S., J. Agric. Chem. Soc. (Japan), 29, 400, 404 (1955).

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ROLINSON, G., BATCHELOR, F., BUTTERWORTH, D. et al. Formation of 6-Aminopenicillanic Acid from Penicillin by Enzymatic Hydrolysis. Nature 187, 236–237 (1960). https://doi.org/10.1038/187236a0

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