Abstract
Vaccines against important enteric pathogens such as rotavirus and poliovirus have shown lower efficacy in some populations. The application of new technologies and diverse scientific disciplines are needed to realize the promise of truly universal and effective solutions to combat those and other enteric diseases.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Diarrheal disease and enteric infections in LMIC communities: how big is the problem?
Tropical Diseases, Travel Medicine and Vaccines Open Access 19 July 2016
-
Comparison of impact and cost-effectiveness of rotavirus supplementary and routine immunization in a complex humanitarian emergency, Somali case study
Conflict and Health Open Access 09 February 2015
-
Health impact of probiotics - vision and opportunities
Gut Pathogens Open Access 12 March 2012
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Richardson, V. et al. N. Engl. J. Med. 362, 299–305 (2010).
Grassly, N.C. et al. Science 314, 1150–1153 (2006).
Grassly, N.C. et al. J. Infect. Dis. 200, 794–801 (2009).
Grassly, N.C. et al. J. Infect. Dis. 201, 1535–1543 (2010).
Paul, Y. Vaccine 27, 3700–3703 (2009).
Madhi, S.A. et al. N. Engl. J. Med. 362, 289–298 (2010).
Patel, M. et al. J. Infect. Dis. 200, S39–S48 (2009).
Petri, W.A. Jr. et al. J. Clin. Invest. 118, 1277–1290 (2008).
Moon, S.S. et al. Pediatr. Infect. Dis. J. 10.1097/INF.0b013e3181e232ea (2010).
Patel, M. et al. J. Am. Med. Assoc. 301, 2243–2251 (2009).
Duerkop, B.A., Vaishnava, S. & Hooper, L.V. Immunity 31, 368–376 (2009).
Hooper, L.V. & Macpherson, A.J. Nat. Rev. Immunol. 10, 159–169 (2010).
Fagundes Neto, U., Martins, M.C., Lima, F.L., Patricio, F.R. & Toledo, M.R. J. Am. Coll. Nutr. 13, 51–56 (1994).
Lagos, R. et al. J. Infect. Dis. 180, 1709–1712 (1999).
Cooper, P.J. et al. J. Infect. Dis. 182, 1199–1206 (2000).
Gotuzzo, E. et al. Infect. Immun. 61, 3994–3997 (1993).
Lastra, M.D., Pastelin, R., Herrera, M.A., Orihuela, V.D. & Aguilar, A.E. Arch. Med. Res. 28, 67–72 (1997).
Shinde, P., Dass, R.S., Garg, A.K., Chaturvedi, V.K. & Kumar, R. Biol. Trace Elem. Res. 112, 247–262 (2006).
Sheikh, A. et al. J. Nutr. 140, 1049–1056 (2010).
Wang, C. & Kang, S.G. J. Immunol. 184, 5519–5526 (2010).
Newport, M.J. et al. Genes Immun. 5, 122–129 (2004).
Marchant, A. et al. J. Infect. Dis. 193, 1598–1605 (2006).
Tishkoff, S.A. et al. Science 324, 1035–1044 (2009).
Reich, D., Thangaraj, K., Patterson, N., Price, A.L. & Singh, L. Nature 461, 489–494 (2009).
Feero, W.G., Guttmacher, A.E. & Collins, F.S. N. Engl. J. Med. 362, 2001–2011 (2010).
Acknowledgements
We thank all the speakers and participants for their participation at the meeting, with a special thanks to all presenters cited here for their contributions to this commentary. The views expressed in this article do not necessarily reflect those of all convening participants.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Serazin, A., Shackelton, L., Wilson, C. et al. Improving the performance of enteric vaccines in the developing world. Nat Immunol 11, 769–773 (2010). https://doi.org/10.1038/ni0910-769
Issue Date:
DOI: https://doi.org/10.1038/ni0910-769
This article is cited by
-
Rotavirus epidemiology and vaccine demand: considering Bangladesh chapter through the book of global disease burden
Infection (2018)
-
Diarrheal disease and enteric infections in LMIC communities: how big is the problem?
Tropical Diseases, Travel Medicine and Vaccines (2016)
-
Comparison of impact and cost-effectiveness of rotavirus supplementary and routine immunization in a complex humanitarian emergency, Somali case study
Conflict and Health (2015)
-
Correlates of protection against human rotavirus disease and the factors influencing protection in low-income settings
Mucosal Immunology (2015)
-
Genomic correlates of variability in immune response to an oral cholera vaccine
European Journal of Human Genetics (2013)