Article
Oncologic Issues and Kidney Transplantation: A Review of Frequency, Mortality, and Screening

https://doi.org/10.1053/j.ackd.2013.07.003Get rights and content

Kidney transplant recipients are at increased risk for development of malignancy compared with the general population, and malignancies occur at an earlier age. This increased risk, as expressed by the standard incidence ratio (SIR), varies widely, but it is highest in malignancies triggered by oncogenic viruses. For other cancers, this increased risk is the direct consequence of immunosuppressants promoting tumor growth and lowering immune system tumor surveillance. In this review, we briefly discuss the common malignancies with increased risk after kidney transplantation, explore the pros and cons associated with screening, and summarize current prevention and treatment recommendations.

Key Words

Kidney transplant
Malignancy
Immunosuppression
Cancer screening

Cited by (0)

Financial Disclosure: The authors declare that they have no relevant financial interests.

View Abstract