Abstract
We report the median cDNA viral load of norovirus genogroup II is >100-fold higher than that of genogroup I in the fecal specimens of patients with norovirus-associated gastroenteritis. We speculate that increased cDNA viral load accounts for the higher transmissibility of genogroup II strains through the fecal-oral route.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Caliciviridae Infections / virology
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Child
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Child, Preschool
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DNA, Complementary / analysis
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DNA, Viral / analysis
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Feces / virology*
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Female
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Gastroenteritis / virology*
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Humans
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Infant
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Male
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Middle Aged
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Norovirus / classification
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Norovirus / genetics
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Norovirus / isolation & purification*
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Viral Load
Substances
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DNA, Complementary
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DNA, Viral