Abstract
Neurological signs are observed in 20-50% of cases of Wegener's granulomatosis consisting of peripheral and cranial neuropathy, and central nervous system involvement during the disease and rarely as initial symptom. We report here a case of thoracic spinal cord compression due to dural masses in a patient with a previous presumptive diagnosis of microscopic polyangiitis indicating Wegener's granulomatosis on histological examination. No other site of involvement was found. Slight clinical improvement was observed under immunosuppressive treatment probably because of spinal cord vessels lesions.
MeSH terms
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Aged
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Biopsy, Needle
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Cyclophosphamide / administration & dosage
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Diagnosis, Differential
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Drug Therapy, Combination
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Female
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Follow-Up Studies
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Granulomatosis with Polyangiitis / complications*
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Granulomatosis with Polyangiitis / diagnosis*
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Granulomatosis with Polyangiitis / drug therapy
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Humans
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Immunohistochemistry
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Magnetic Resonance Imaging
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Methylprednisolone / administration & dosage
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Risk Assessment
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Spinal Cord Compression / diagnosis
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Spinal Cord Compression / etiology*
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Spinal Cord Compression / therapy
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Thoracic Vertebrae
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Treatment Outcome
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Vasculitis / diagnosis*
Substances
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Cyclophosphamide
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Methylprednisolone