Referral of patients with iron deficiency anaemia under the lower gastrointestinal two-week wait rule

Colorectal Dis. 2008 Mar;10(3):294-7. doi: 10.1111/j.1463-1318.2007.01364.x. Epub 2007 Aug 31.

Abstract

Objective: One of the 2-week wait (2WW) criteria for suspected lower gastrointestinal cancer states that patients should be referred who have iron deficiency anaemia (IDA) without obvious cause [Haemoglobin (Hb) <11 g/dl men, <10 g/dl postmenopausal women].

Aim: Our aim was to find the proportion of patients referred as a 2WW not meeting the criteria, and the cost accrued by unnecessary referral.

Method: Patients referred over 1 year were identified using the hospitals cancer database. Haematology, haematinics, coeliac serology and cancer status were recorded for each patient.

Results: A total of 204 patients were referred. In total, only 22/204 patients (10.8%) met all the necessary criteria for diagnosis and investigation of IDA prior to referral. As only 43/204 (21.1%) had been assessed for coeliac serology, this accounted for the majority of incomplete referrals. Excluding coeliac serology, only 127 (62.3%) met 2WW criteria for IDA. Of the remaining 77 patients, 57 (74%) patients did not meet the 2WW criteria on Hb alone and 35/77 were referred with no evidence of IDA. 12/127 (9.4%) patients were diagnosed with colorectal cancer. No cancers were detected in patients without BSG evidence of IDA, although one patient did not meet the criteria on Hb level alone.

Conclusion: Although iron deficiency is a good marker for gastrointestinal cancer, it is evident that 2WW referral guidelines are not being followed. 89.2% of referrals are inappropriate according to guidelines. This not only has considerable workload and financial implications but could be potentially detrimental to patient health.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Anemia, Iron-Deficiency / complications
  • Anemia, Iron-Deficiency / diagnosis*
  • Cohort Studies
  • Cost-Benefit Analysis
  • Endoscopy, Gastrointestinal / economics
  • Female
  • Follow-Up Studies
  • Gastrointestinal Neoplasms / diagnosis*
  • Gastrointestinal Neoplasms / epidemiology
  • Gastrointestinal Neoplasms / etiology
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Practice Guidelines as Topic
  • Referral and Consultation / economics
  • Referral and Consultation / statistics & numerical data*
  • Registries
  • Risk Assessment
  • Severity of Illness Index
  • Sex Distribution
  • Time Factors
  • United Kingdom
  • Unnecessary Procedures / economics*
  • Unnecessary Procedures / statistics & numerical data
  • Waiting Lists*