Once is not enough: clinical trials in sepsis

MeSH terms

• Adrenal Cortex Hormones / therapeutic use
• Anti-Infective Agents / therapeutic use*
• Antibodies, Monoclonal / therapeutic use
• Clinical Trials, Phase III as Topic* / ethics
• Clinical Trials, Phase III as Topic* / methods
• Drug Industry / ethics
• Humans
• Insulin / therapeutic use
• Multicenter Studies as Topic* / ethics
• Multicenter Studies as Topic* / methods
• Placebos
• Protein C / therapeutic use*
• Randomized Controlled Trials as Topic* / ethics
• Randomized Controlled Trials as Topic* / methods
• Receptors, Interleukin-1 / antagonists & inhibitors
• Recombinant Proteins / therapeutic use
• Research Design*
• Shock, Septic / drug therapy*
• Shock, Septic / mortality
• United States / epidemiology
• United States Food and Drug Administration