This article will provide an overview of the psychosocial and cognitive problems that people with epilepsy (PWE) experience as consequence of the condition and its treatment. Psychosocial problems will be discussed in light of how they impact on quality of life. The review will discuss the stigma, myths and stereotypes that PWE encounter and the implications of these for important psychological outcomes including; anxiety, depression, self-esteem, sense of mastery and cognitive dysfunction. The latter part of the article will focus on psychosocial factors including social isolation, interpersonal and family relationships and employment. The overall aim is to provide the reader with a general overview of the sort of factors that can impede social functioning in PWE with particular emphasis on the problems encountered in adults.