Association between falls and high-risk medication use in hospitalized Asian elderly patients

Geriatr Gerontol Int. 2009 Sep;9(3):276-81. doi: 10.1111/j.1447-0594.2009.00533.x.

Abstract

Aim: Most studies looking at the relation between medication use and fall among the hospitalized elderly patients, were done in Western countries. So, a study was planned to investigate the role of medications in causing falls in hospitalized Asian elderly patients.

Methods: Case note review was done for all patients age 65 years and above, who fell at least once during their hospital stay over a 12-month period. Information obtained from the case notes included: (i) demographic information; (ii) Modified Morse Fall scale; (iii) circumstances and time of fall; and (iv) medication use. From the hospital admission database, an age- and sex-matched control group was selected for comparison.

Results: Over the 12-month study period, 298 patients met the study criteria. Average age of the patients was 75.8 years, 60.4% were male and 84.9% were Chinese. Multivariate analysis showed that fallers had longer lengths of stay and were more likely to have a history of falls. Fallers were also more likely to be taking hypnotics, cough preparations and anti-platelets, but less likely to be taking paracetamol. Fallers were on fewer medications.

Conclusion: Elderly hospitalized patients on hypnotic drugs, cough preparations and anti-platelets were more likely to fall. Appropriate usage of analgesics, especially paracetamol, to relieve pain may reduce falls.

Publication types

  • Comparative Study

MeSH terms

  • Accidental Falls / statistics & numerical data*
  • Acetaminophen / adverse effects
  • Aged
  • Aged, 80 and over
  • Analgesics, Non-Narcotic / adverse effects*
  • Asia
  • Female
  • Humans
  • Hypnotics and Sedatives / adverse effects*
  • Male
  • Platelet Aggregation Inhibitors / adverse effects*
  • Risk Factors

Substances

  • Analgesics, Non-Narcotic
  • Hypnotics and Sedatives
  • Platelet Aggregation Inhibitors
  • Acetaminophen