Metabolism, gliomas, and IDH1

N Engl J Med. 2010 Mar 25;362(12):1144-5. doi: 10.1056/NEJMcibr0912922.
No abstract available

MeSH terms

  • Brain Neoplasms / genetics*
  • Brain Neoplasms / metabolism
  • Genetic Markers
  • Glioma / genetics*
  • Glioma / metabolism
  • Glutarates / metabolism*
  • Humans
  • Isocitrate Dehydrogenase / genetics*
  • Isocitrate Dehydrogenase / metabolism
  • Isocitrates / metabolism*
  • Ketoglutaric Acids / metabolism*
  • Metabolism, Inborn Errors* / genetics
  • Mutant Proteins / metabolism
  • Mutation
  • Prognosis

Substances

  • Genetic Markers
  • Glutarates
  • Isocitrates
  • Ketoglutaric Acids
  • Mutant Proteins
  • alpha-hydroxyglutarate
  • isocitric acid
  • Isocitrate Dehydrogenase
  • IDH1 protein, human