The SAPHO acronym corresponds to a group of benign conditions that combine osteoarticular and skin involvement whose diagnosis is mainly clinical and is supported by imaging findings. The bone scintigraphy has a relevant role due to its sensitivity and early detection ability. We present 8 patients with SAPHO syndrome whose clinical involvement began with skin manifestations. All of them had palmoplantar pustulosis, either of recent onset or outbreak evolution. Some had associated osteoarticular pain in shoulders, sternum, lumbar area or limbs. Bone scintigraphy with Tc-99m-diphosphonate showed pathological findings in all the patients, detecting sternoclavicular joint damage, this being the most frequent involvement in 7 of them, and also in other less usual localizations.
2009 Elsevier España, S.L. y SEMNIM. All rights reserved.