3 cases of Crohn's disease whose first manifestation was fever preceding intestinal symptoms, 3, 12, and 36 months respectively, the intestinal symptoms, are presented. Apart from fever, one of our cases had multiple extraintestinal symptoms these being of pancreatic, hepatic, mucocutaneous, bone and ocular origin. We insist on the heterogeneous onset of the disease which forced the clinician to maintain this disease on the long list of prolonged febrile illnesses causes.