The disproportionate risk burden of CT scanning on females and younger adults in Australia: a retrospective cohort study

Aust N Z J Public Health. 2014 Oct;38(5):441-8. doi: 10.1111/1753-6405.12278.

Abstract

Objectives: To explore the interaction of computed tomography (CT) use, dose and radiation risk of Australian Medicare-funded CT scanning and the impact on cancer incidence and mortality.

Methods: This retrospective cohort study used records of Medicare subsidised CT scans in Australia (2006/07 to 2011/12) and Australian CT dosimetry. The annual number, rate and adjusted likelihood of CT were determined for gender, age and examination type. Incident cancer and cancer-related mortality attributable to CT in Australia were estimated using lifetime attributable risk coefficients, dosimetry and scan numbers.

Results: The number of CT scans increased by 36% from 2006/07 to 2011/12. Only patients aged 0-4 years did not present an increase in CT scanning rates. Females were 11% more likely to be scanned than males. Head, abdomen/pelvis and spine CT scans were the most likely areas scanned. Females were attributed 61% of both incident cancers and cancer-related mortality from 55% of scans performed. Patients aged 15-44 years were attributed 37% of incident cancers and 30% of cancer-related mortality from 26% of CT scans.

Conclusions: CT in Australia is increasing, including in groups at higher risk from ionising radiation. This presents a complex set of risk/benefit considerations for clinicians and policy makers.

Keywords: cancer risk; computed tomography; service utilisation.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Australia / epidemiology
  • Child
  • Child, Preschool
  • Cost of Illness
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Middle Aged
  • Neoplasms, Radiation-Induced / epidemiology*
  • Neoplasms, Radiation-Induced / etiology
  • Radiation Dosage
  • Retrospective Studies
  • Risk Assessment / methods*
  • Risk Factors
  • Sex Distribution
  • Socioeconomic Factors
  • Tomography, X-Ray Computed / adverse effects*
  • Tomography, X-Ray Computed / statistics & numerical data*
  • Young Adult