Reducing LDL with PCSK9 Inhibitors--The Clinical Benefit of Lipid Drugs

N Engl J Med. 2015 Oct 22;373(17):1588-91. doi: 10.1056/NEJMp1508120. Epub 2015 Oct 7.
No abstract available

MeSH terms

  • Advisory Committees
  • Antibodies, Monoclonal / therapeutic use*
  • Antibodies, Monoclonal, Humanized
  • Anticholesteremic Agents / pharmacology
  • Anticholesteremic Agents / therapeutic use*
  • Cardiovascular Diseases / prevention & control*
  • Cholesterol, LDL / blood*
  • Drug Approval
  • Humans
  • Hypercholesterolemia / drug therapy*
  • Proprotein Convertase 9
  • Proprotein Convertases / antagonists & inhibitors*
  • Risk Factors
  • Serine Endopeptidases
  • United States
  • United States Food and Drug Administration

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Humanized
  • Anticholesteremic Agents
  • Cholesterol, LDL
  • PCSK9 protein, human
  • Proprotein Convertase 9
  • Proprotein Convertases
  • Serine Endopeptidases
  • evolocumab
  • alirocumab