Lesson of the month 1: broken heart in the intensive care unit

Clin Med (Lond). 2014 Aug;14(4):447-8. doi: 10.7861/clinmedicine.14-4-447.

Abstract

Takotsubo cardiomyopathy (TCM) is an unusual form of acute cardiomyopathy showing left ventricular apical ballooning. TCM can masquerade as ST elevation myocardial infarction (STEMI). TCM usually occurs following a variety of emotional stressors, but physical stressors can also trigger the condition, as highlighted by the present case. TCM can occur after an acute medical illness; therefore, physicians should be aware of this condition as a potential cause of inotrope-resistant hypotension. In patients with hypotension and moderate-to-severe left ventricular outflow tract (LVOT) obstruction, inotropic agents should be avoided, because they can worsen the degree of obstruction. Instead, beta-blockers are preferred, because they are capable of resolving the obstruction and consequently improve the haemodynamics.

Keywords: ST segment elevation; Takotsubo cardiomyopathy; intensive care unit; physical stress.

Publication types

  • Case Reports

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Electrocardiography*
  • Humans
  • Intensive Care Units
  • Male
  • Middle Aged
  • Takotsubo Cardiomyopathy / diagnosis*
  • Takotsubo Cardiomyopathy / drug therapy

Substances

  • Adrenergic beta-Antagonists