User profiles for A Iyer

Arun Iyer, PhD, Associate Professor of Pharmaceutical Sciences

- Verified email at wayne.edu - Cited by 13085

Ashwin K. Iyer

- Verified email at ualberta.ca - Cited by 4701

Ananth Iyer

- Verified email at buffalo.edu - Cited by 3880

Exploiting the enhanced permeability and retention effect for tumor targeting

AK Iyer, G Khaled, J Fang, H Maeda - Drug discovery today, 2006 - Elsevier
Of the tumor targeting strategies, the enhanced permeability and retention (EPR) effect of
macromolecules is a key mechanism for solid tumor targeting, and considered a gold standard …

[HTML][HTML] PD-1 and PD-L1 checkpoint signaling inhibition for cancer immunotherapy: mechanism, combinations, and clinical outcome

…, R Alzhrani, K Bhise, SK Kashaw, AK Iyer - Frontiers in …, 2017 - frontiersin.org
Several cancers are highly refractory to conventional chemotherapy. The survival of tumors
in several cases is assisted by checkpoint immunomodulation to maintain the imbalance …

Affirmative action: Psychological data and the policy debates.

FJ Crosby, A Iyer, S Clayton, RA Downing - American Psychologist, 2003 - psycnet.apa.org
The authors bring psychological research to bear on an examination of the policy of affirmative
action. They argue that data from many studies reveal that affirmative action as a policy …

Beyond the imitation game: Quantifying and extrapolating the capabilities of language models

…, A Dsouza, A Slone, A Rahane, AS Iyer… - arXiv preprint arXiv …, 2022 - arxiv.org
Language models demonstrate both quantitative improvement and new qualitative
capabilities with increasing scale. Despite their potentially transformative impact, these new …

Planar negative refractive index media using periodically LC loaded transmission lines

GV Eleftheriades, AK Iyer… - IEEE transactions on …, 2002 - ieeexplore.ieee.org
Recent demonstrations of negative refraction utilize three-dimensional collections of
discrete periodic scatterers to synthesize artificial dielectrics with simultaneously negative …

[HTML][HTML] An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma

P Sumazin, X Yang, HS Chiu, WJ Chung, A Iyer… - Cell, 2011 - cell.com
By analyzing gene expression data in glioblastoma in combination with matched microRNA
profiles, we have uncovered a posttranscriptional regulation layer of surprising magnitude, …

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

…, S Balosso, T Ravizza, J Liu, E Aronica, AM Iyer… - Nature medicine, 2010 - nature.com
Brain inflammation is a major factor in epilepsy, but the impact of specific inflammatory mediators
on neuronal excitability is incompletely understood. Using models of acute and chronic …

Maintaining group memberships: Social identity continuity predicts well-being after stroke

C Haslam, A Holme, SA Haslam, A Iyer… - Neuropsychological …, 2008 - Taylor & Francis
A survey study of patients recovering from stroke (N = 53) examined the extent to which
belonging to multiple groups prior to stroke and the maintenance of those group memberships (…

Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients

AS Iyer, FK Jones, A Nodoushani, M Kelly… - Science …, 2020 - science.org
We measured plasma and/or serum antibody responses to the receptor-binding domain (RBD)
of the spike (S) protein of SARS-CoV-2 in 343 North American patients infected with …

[HTML][HTML] Components of bottom-up gaze allocation in natural images

RJ Peters, A Iyer, L Itti, C Koch - Vision research, 2005 - Elsevier
Recent research [Parkhurst, D., Law, K., & Niebur, E., 2002. Modeling the role of salience in
the allocation of overt visual attention. Vision Research 42 (1) (2002) 107–123] showed that …