The first pyrethroid pesticide, allethrin, was identified in 1949. Allethrin and other pyrethroids
with a basic cyclopropane carboxylic ester structure are type I pyrethroids. The insecticidal …

Chemokines and their receptors are involved in the pathogenesis of diseases ranging from
asthma to AIDS. Chemokine receptors are G-protein-coupled serpentine receptors that …

▪ Abstract Immune modulators such as cytokines and growth factors exert their biological
activity through high-affinity interactions with cell-surface receptors, thereby activating specific …

Background— Monocytes are critical mediators of atherogenesis. Deletion of individual
chemokines or chemokine receptors leads to significant but only partial inhibition of lesion …

The complex pathophysiology of lung allergic inflammation and bronchial hyperresponsiveness
(BHR) that characterize asthma is achieved by the regulated accumulation and …

During organogenesis, immunosurveillance, and inflammation, chemokines selectively
recruit leukocytes by activating seven-transmembrane-spanning receptors. It has been …

The chemokines platelet factor 4 (PF4) and RANTES (regulated on activation normal T cell
expressed and secreted) are secreted by activated platelets and influence multiple cell types …

One hundred cases of severe paracetamol poisoning were treated with intravenous N-acetylcysteine
(acetyl-cysteine). There was virtually complete protection against liver damage in …

Chemokines selectively recruit and activate a variety of cells during inflammation. Interactions
between cell surface glycosaminoglycans (GAGs) and chemokines drive the formation of …

The involvement of chemokines in inflammation is well established, but their functional role
in disease progression, and particularly in the development of fibrosis, is not yet understood. …