Objectives. We examined the probability of an obese person attaining normal body weight.
Methods. We drew a sample of individuals aged 20 years and older from the United Kingdom’…

Objective To assess the impact of communicating DNA based disease risk estimates on risk-reducing
health behaviours and motivation to engage in such behaviours. Design …

In March, 2020, WHO declared COVID-19 a global pandemic. At the time of writing, the UK
has the highest number of recorded fatalities in Europe, with London regarded as the …

Background The increasing prevalence of type 2 diabetes poses a major public health
challenge. Population-based screening and early treatment for type 2 diabetes could reduce this …

Background Proliferative diabetic retinopathy is the most common cause of severe sight
impairment in people with diabetes. Proliferative diabetic retinopathy has been managed by …

Dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) are adrenal precursors of
steroid biosynthesis and centrally acting neurosteroids. Glucocorticoid and mineralocorticoid …

OBJECTIVE To explore the prevalence of lipid abnormalities and their relationship with
albumin excretion and microalbuminuria in adolescents with type 1 diabetes. RESEARCH …

Background: Identification of a genetic basis underlying certain types of cancer has led to
an increase in demand for genetic counseling about individual risks of the disease. We …

Importance Screening for prostate cancer using prostate-specific antigen (PSA) testing can
lead to problems of underdiagnosis and overdiagnosis. Short, noncontrast magnetic …

Objective To determine whether the incidence of pneumonia, peritonsillar abscess,
mastoiditis, empyema, meningitis, intracranial abscess, and Lemierre’s syndrome is higher in …