Objective Inhibition of food intake and glucose homeostasis are both promoted when nutrients
stimulate enteroendocrine cells (EEC) to release gut hormones. Several specific nutrient …

Background Atrial fibrillation (AF) is a common cardiac arrhythmia, which is often associated
with underlying risk factors and undiagnosed conditions, including congenital heart disease…

A 36-year-old woman presented with recurrent pulmonary emboli (PE) despite oral
anticoagulation. She was a type I diabetic with severe gastroparesis requiring insertion of multiple …

Aims Opioids are commonly used on the intensive care unit (ICU) but are associated with a
high incidence of constipation, often resistant to conventional laxative treatment. Recently …

On the 6th July 2021, Boehringer-Ingelheim announced the preliminary positive results of
the EMPEROR-Preserved trial of empagliflozin for patients with heart failure (HF) with a …

The 2012 European Society of Cardiology (ESC) Heart Failure (HF) guidelines recommended,
in its 61 pages, the use of three different drug classes for the treatment of “systolic” HF …

Autonomic Dysreflexia (AD) is a clinical emergency characterised by an uncontrolled
sympathetic response in patients with spinal cord injuries occurring at or above the level of T6. …

Aims Cardiac implantable electronic devices (CIEDs) are the mainstay of care in patients
with life-threatening ventricular arrhythmia, severe left ventricular impairment or symptomatic …

Background A ‘malignant polyp’contains cancer cells that have breached the mucosa. Usually
this refers to a polyp that is resected endoscopically and appears benign, but contains …

Aims A simulation-based training course was designed with the aim of improving confidence
of core medical trainees (CMTs) in managing emergency presentations and cardiac arrest. …