Objective To compare 5-year lesion recurrence rates in primary nodular basal cell carcinoma
treated with topical methyl aminolevulinate photodynamic therapy (PDT) or simple excision …

Molluscum contagiosum virus is an important human skin pathogen: it can cause disfigurement
and suffering in children, in adults it is less common and often sexually transmitted. …

Background Erythropoietic protoporphyria (EPP) is a rare inherited photodermatosis that
causes lifelong painful photosensitivity. Neither its full clinical spectrum nor its impact on quality …

1.0 Background Psoriasis is a common, chronic inflammatory skin disease which typically
follows a relapsing and remitting course, and is associated with joint disease in approximately …

The porphyrias are a group of disorders caused by defects in haem biosynthesis (fig 1). Of
the seven main types of porphyria recognised, two are characterised by associated liver …

Microneedle delivery of nucleic acids, in particular plasmid DNA (pDNA), to the skin
represents a potential new approach for the clinical management of genetic skin diseases and …

Azathioprine has been available as an immunosuppressive agent for over 40 years, and
current routine usage in dermatology is not restricted to licensed indications. Advances in …

Background Psoriasis is a common, persistent, relapsing inflammatory skin disease that can
be associated with significant morbidity. Quality of life studies in psoriasis reveal a negative …

All reported mutations in ALAS2, which encodes the rate-regulating enzyme of erythroid heme
biosynthesis, cause X-linked sideroblastic anemia. We describe eight families with ALAS2 …

Background Erythropoietic protoporphyria is a severe photodermatosis that is associated
with acute phototoxicity. Patients with this condition have excruciating pain and a markedly …