User profiles for Alex Hoffman
Alexander F. Hoffman, Ph.D.National Institutes of Health, National Institute on Drug Abuse Intramural Research Program Verified email at intra.nida.nih.gov Cited by 6964 |
Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo
BJ Hoffer, A Hoffman, K Bowenkamp, P Huettl… - Neuroscience …, 1994 - Elsevier
Fischer 344 rats were unilaterally injected into the medial forebrain bundle with 6-hydroxydopamine
(6-OHDA). Apomorphine-induced rotational behavior was used to select animals …
(6-OHDA). Apomorphine-induced rotational behavior was used to select animals …
Glial cell line-derived neurotrophic factor augments midbrain dopaminergic circuits in vivo
Recently, a novel glial cell line-derived neurotrophic factor (GDNF) has been identified,
cloned, and shown to have potent survival- and growth-promoting activity on fetal rat midbrain …
cloned, and shown to have potent survival- and growth-promoting activity on fetal rat midbrain …
Branchial elimination of superhydrophobic organic compounds by rainbow trout (Oncorhynchus mykiss)
PN Fitzsimmons, JD Fernandez, AD Hoffman… - Aquatic toxicology, 2001 - Elsevier
The branchial elimination of pentachloroethane and four congeneric polychlorinated biphenyls
by rainbow trout was measured using a fish respirometer-metabolism chamber and an …
by rainbow trout was measured using a fish respirometer-metabolism chamber and an …
Can a novel clinical risk score improve pneumonia prediction in acute stroke care? A UK multicenter cohort study
Background Pneumonia frequently complicates stroke and has a major impact on outcome.
We derived and internally validated a simple clinical risk score for predicting stroke‐…
We derived and internally validated a simple clinical risk score for predicting stroke‐…
Mechanisms of cannabinoid inhibition of GABAASynaptic transmission in the hippocampus
AF Hoffman, CR Lupica - Journal of Neuroscience, 2000 - Soc Neuroscience
The localization of cannabinoid (CB) receptors to GABAergic interneurons in the hippocampus
indicates that CBs may modulate GABAergic function and thereby mediate some of the …
indicates that CBs may modulate GABAergic function and thereby mediate some of the …
[HTML][HTML] Powerful cocaine-like actions of 3, 4-methylenedioxypyrovalerone (MDPV), a principal constituent of psychoactive 'bath salts' products
…, KR Lehner, EB Thorndike, AF Hoffman… - …, 2013 - nature.com
The abuse of psychoactive ‘bath salts’ containing cathinones such as 3, 4-methylenedioxypyrovalerone
(MDPV) is a growing public health concern, yet little is known about their …
(MDPV) is a growing public health concern, yet little is known about their …
[HTML][HTML] Socioeconomic disparities in first stroke incidence, quality of care, and survival: a nationwide registry-based cohort study of 44 million adults in England
BD Bray, L Paley, A Hoffman, M James… - The Lancet Public …, 2018 - thelancet.com
Background We aimed to estimate socioeconomic disparities in the incidence of hospitalisation
for first-ever stroke, quality of care, and post-stroke survival for the adult population of …
for first-ever stroke, quality of care, and post-stroke survival for the adult population of …
Evaluation of log KOW and tissue lipid content as predictors of chemical partitioning to fish tissues
SL Bertelsen, AD Hoffman, CA Gallinat… - … and Chemistry: An …, 1998 - Wiley Online Library
In vitro equilibrium chemical partition coefficients were determined for six chemicals in
selected tissues from four species of fish. Log‐transformed values were then regressed in …
selected tissues from four species of fish. Log‐transformed values were then regressed in …
The economic burden of stroke care in England, Wales and Northern Ireland: Using a national stroke register to estimate and report patient-level health economic …
…, A Desikan, D Wonderling, A Hoffman… - European stroke …, 2018 - journals.sagepub.com
Introduction Stroke registries are used in many settings to measure stroke treatment and
outcomes, but rarely include data on health economic outcomes. We aimed to extend the …
outcomes, but rarely include data on health economic outcomes. We aimed to extend the …
[HTML][HTML] Associations between stroke mortality and weekend working by stroke specialist physicians and registered nurses: prospective multicentre cohort study
…, J Campbell, GC Cloud, M James, A Hoffman… - PLoS …, 2014 - journals.plos.org
Background Observational studies have reported higher mortality for patients admitted on
weekends. It is not known whether this “weekend effect” is modified by clinical staffing levels …
weekends. It is not known whether this “weekend effect” is modified by clinical staffing levels …