Migraine is a disabling primary headache disorder that directly affects more than one billion
people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed …

Background A previous European Headache Federation (EHF) guideline addressed the use
of monoclonal antibodies targeting the calcitonin gene-related peptide (CGRP) pathway to …

Idiopathic intracranial hypertension is a disorder characterised by raised intracranial
pressure that predominantly affects young, obese women. Pathogenesis has not been fully …

Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine…

RESEARCH Page 1 RESEARCH Low energy diet and intracranial pressure in women with
idiopathic intracranial hypertension: prospective cohort study Alexandra J Sinclair, MRC …

The aim was to capture interdisciplinary expertise from a large group of clinicians, reflecting
practice from across the UK and further, to inform subsequent development of a national …

Cerebrospinal fluid is vital for normal brain function. Changes to the composition, flow, or
pressure can cause a variety of neurological symptoms and signs. Equally, disorders of …

A minority of headache patients have a secondary headache disorder. The medical literature
presents and promotes red flags to increase the likelihood of identifying a secondary …

Idiopathic intracranial hypertension (IIH) is a rare but important disease associated with
significant morbidity. There is an expected rise in prevalence in line with the escalating global …

Introduction Despite advances in the management of headache disorders, some patients with
migraine do not experience adequate pain relief with acute and preventive treatments. It is …