User profiles for Amyn Lalji

Amyn Lalji

CBM International
Verified email at cbm.org
Cited by 847

Algorithm-based management of patients with gastrointestinal symptoms in patients after pelvic radiation treatment (ORBIT): a randomised controlled trial

HJN Andreyev, BE Benton, A Lalji, C Norton… - The Lancet, 2013 - thelancet.com
Background Chronic gastrointestinal symptoms after pelvic radiotherapy are common,
multifactorial in cause, and affect patients' quality of life. We assessed whether such patients could …

[HTML][HTML] Randomized controlled trial of dietary fiber for the prevention of radiation-induced gastrointestinal toxicity during pelvic radiotherapy

L Wedlake, C Shaw, H McNair, A Lalji… - The American journal of …, 2017 - Elsevier
Background Therapeutic radiotherapy is an important treatment of pelvic cancers. Historically,
low-fiber diets have been recommended despite a lack of evidence and potentially …

[HTML][HTML] Evaluating the efficacy of statins and ACE-inhibitors in reducing gastrointestinal toxicity in patients receiving radiotherapy for pelvic malignancies

LJ Wedlake, F Silia, B Benton, A Lalji, K Thomas… - European journal of …, 2012 - Elsevier
INTRODUCTION: 3-Hydroxy-methylglutaryl coenzyme-A reductase inhibitors (statins) improve
survival following pelvic irradiation for cancer. Large studies suggest that patients with …

Effectiveness and tolerability of colesevelam hydrochloride for bile-acid malabsorption in patients with cancer: a retrospective chart review and patient questionnaire

L Wedlake, K Thomas, A Lalji, C Anagnostopoulos… - Clinical …, 2009 - Elsevier
Background: Commercially available bile-acid sequestrants are not well tolerated by >80%
of patients. Objective: The aim of the present study was to assess the effectiveness and …

Predicting late effects of pelvic radiotherapy: is there a better approach?

LJ Wedlake, K Thomas, A Lalji, P Blake… - International Journal of …, 2010 - Elsevier
PURPOSE: Significant chronic symptoms following pelvic radiotherapy occur more frequently
than commonly realized. Predictive factors for the development of late symptoms are …

[HTML][HTML] Bile acid malabsoption: a forgotten diagnosis?

U Khalid, A Lalji, R Stafferton, J Andreyev - Clinical medicine, 2010 - ncbi.nlm.nih.gov
Bile acid malabsorption (BAM) is never life threatening but can cause chronic symptoms. A
survey of senior British gastroenterologists was conducted to examine their approach to …

[HTML][HTML] Management of bile acid malabsorption using low-fat dietary interventions: a useful strategy applicable to some patients with diarrhoea-predominant irritable …

L Watson, A Lalji, S Bodla, A Muls, HJN Andreyev… - Clinical …, 2015 - ncbi.nlm.nih.gov
This study evaluates the efficacy of low-fat dietary interventions in the management of
gastrointestinal (GI) symptoms due to bile acid malabsorption. In total, 40 patients with GI …

[HTML][HTML] The efficacy of a low-fat diet to manage the symptoms of bile acid malabsorption–outcomes in patients previously treated for cancer

A Jackson, A Lalji, M Kabir, A Muls, C Gee… - Clinical …, 2017 - ncbi.nlm.nih.gov
Dietary fat ingestion triggers bile secretion into the gastrointestinal tract. Bile acid malabsorption
affects> 1% of the population, causing loose stool and other gastrointestinal symptoms. …

[HTML][HTML] The FOCCUS study: a prospective evaluation of the frequency, severity and treatable causes of gastrointestinal symptoms during and after chemotherapy

HJN Andreyev, A Lalji, K Mohammed, ACG Muls… - Supportive Care in …, 2021 - Springer
Background The underlying mechanisms of chemotherapy-induced gastrointestinal (GI)
symptoms are poorly researched. This study characterised the nature, frequency, severity and …

Outcomes from treating bile acid malabsorption using a multidisciplinary approach

A Gupta, AC Muls, A Lalji, K Thomas, L Watson… - Supportive Care in …, 2015 - Springer
Background & aim Despite bile acid malabsorption affecting >1 % of the population, the
outcomes of treatment are largely unreported. This study evaluated the effectiveness of a …